Reactive oxygen species production and redox state in parthenogenetic and sperm-mediated bovine oocyte activation
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چکیده
منابع مشابه
The impact of reactive oxygen species on bovine sperm fertilizing ability and oocyte maturation.
The objective of this study was to examine the effects of reactive oxygen species (ROS) on bovine sperm function and on the developmental competence of in vitro-matured bovine oocytes. In a first series of experiments, spermatozoa were exposed to ROS generated through the use of the hypoxanthine-xanthine oxidase system +/- catalase prior to the conduct of in vitro fertilization (IVF). Reactive ...
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Reactive oxygen species (ROS) arise through normal cellular aerobic respiration, and, in combination with external sources such as ionizing radiation, cigarette tar and smoke, and particulate matter generated by combustion, can have a profound negative effect on cellular macromolecules such as DNA that may lead to a number of human pathological disorders including accelerated aging and cancer. ...
متن کاملReactive oxygen species in bovine embryo in vitro production.
Oxidative modifications of cell components due to the action of reactive oxygen species (ROS) is one of the most potentially damaging processes for proper cell function. However, in the last few years it has been observed that ROS participate in physiological processes. The aim of this work was to determine ROS generation during in vitro production of bovine embryos. Cumulus-oocyte complexes we...
متن کاملNovel association between sperm reactive oxygen species production, sperm morphological defects, and the sperm deformity index.
OBJECTIVE To examine the relationship between sperm reactive oxygen species (ROS) production and sperm morphology in a group of infertile men and healthy fertile donors. DESIGN A prospective clinical study. SETTING Male infertility clinic, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, and the Reproductive Medicine Unit, Liverpool Women's Hospital, United K...
متن کاملReactive oxygen species and redox compartmentalization
Reactive oxygen species (ROS) formation and signaling are of major importance and regulate a number of processes in physiological conditions. A disruption in redox status regulation, however, has been associated with numerous pathological conditions. In recent years it has become increasingly clear that oxidative and reductive modifications are confined in a spatio-temporal manner. This makes R...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2013
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-13-0017